Long-term survival in a patient with uveal melanoma and liver metastasis.

Uveal melanoma is the most common primary ocular malignancy in whites and represents 70% of all primaryocularmalignancies. Inpatients with metastatic uveal melanoma, the prognosis for those with initial metastasistotheliverisparticularlypoor. The median survival of patients who first develop liver metastasis from uveal melanoma is 5 to 7 months, as compared with 18 months for other initial sites of metastasis. This poor prognosiscontinuesdespitetreatment modalities such as chemoembolization. Wereportacaseofuvealmelanoma with initial metastasis to the liver in a patient who survived for more than 5 years after diagnosis of liver metastasis.